A Comparative Analysis of St-Segment Elevation Myocardial Infarction between Canada and the United States from the North American Covid-19 Stemi Registry

Background: Important healthcare differences exist between the US and Canada. The goal of this investigation is to compare clinical characteristics, treatment strategies and clinical outcomes of STEMI patients with COVID-19 infection treated in the US versus Canada. Methods and Results: The North American COVID-19 Myocardial Infarction (NACMI) registry is a prospective, investigator-initiated study enrolling STEMI patients with documented COVID infection in the US and Canada. The primary end-point is in-hospital mortality. The secondary end-points include stroke, reinfarction and a composite of death, stroke or reinfarction. Of the 767 STEMI-COVID patients, 67 (9%) were from Canada and 669 (91%) from the US. Patients enrolled in Canada were more likely to present with chest pain (79% vs. 54%, p< 0.001), otherwise patients across both countries had comparable presenting demographics (Table 1). The proportion of patients not undergoing coronary angiography was significantly lower in Canada compared with the US (9% vs. 19%, p=0.039);of those who underwent angiography, no significant differences in reperfusion modalities were noted. Compared with the US, patients in Canada had a significantly lower unadjusted risk for in-hospital mortality (15% vs. 29%, p=0.016) and the risk for the composite of death, stroke or re-infarction (15% vs. 31%, p=0.006). Vaccination status was available in Canada 26 / 67 patients (unvaccinated 13, vaccinated 13) and US 328/ 669 patients (unvaccinated 282, vaccinated 46);a strong association between vaccination and adverse clinical composite is noted in both countries (Canada: 3/13, 23% (unvaccinated) vs. 0/13, 0% (vaccinated), p=0.22;and, US: 75/282, 27% (unvaccinated) vs. 6/46, 13% (vaccinated), p=0.048). Conclusion(s): Among patients with STEMI and COVID-19 infection those treated in Canada had higher proportions undergoing angiography and a lower risk of death, stroke or reinfarction. Regardless of geography, vaccination was associated with significantly lower risk of mortality in both countries. [Formula presented] Copyright © 2022

Exploring the correlation between covid-19 and periodontal diseases-An original research

Aim: Purpose of the present research was to assess the co-relation between covid-19 and periodontal disease. Methodology: A case-control study was conducted amongst 150 participants. Patients who had positive real time reverse transcription polymerase chain reaction results for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were included in the case group (n = 79), and patients with negative results were included in the control group (n = 71). The periodontal examination involved recording the plaque scores, calculus scores, tooth mobility, gingival bleeding, probing depth, recession, and clinical attachment level (CAL). Result(s): Logistic regression analysis showed significant associations of mean plaque scores >= 1 (odds ratio (OR), 7.01;95% confidence interval (CI), 1.83 to 26.94), gingivitis (OR, 17.65;95% CI, 5.95 to 52.37), mean CAL >= 2 mm (OR, 8.46;95% CI, 3.47 to 20.63), and severe periodontitis (OR, 11.75;95% CI, 3.89 to 35.49) with COVID-19;these findings were more prevalent in the case group. Conclusion(s): Based on the above mentioned observations, it can be concluded that there is an association between periodontitis severity and COVID-19. Gingival bleeding and dental plaque accumulation are also more frequent among COVID-19 patients. Hence, it is essential to maintain periodontal health and good oral hygiene as an important measure for COVID-19 prevention and management. Copyright © 2022 Ubiquity Press. All rights reserved.

Android based advanced bus reservation system in the pandemic of Covid-19

Social distancing is one of the major requirements of Covid-19. India is a country with a huge population of middle and low financial income and they depend on public transportation to a large extent. In this context, to avoid social distancing while transportation, we propose, android based bus booking system. To achieve this purpose, we have used android studio, because it is an officially developed environment for Android OS. It is built on JetBrains' IntelliJ IDEA software that enables to provide a simple platform to users to check bus availability and reserve it with ease. The parameters like booking the seats between desired source and destination location, desired date, desired type of bus like AC or Non-AC, sleeper or sitting, reserving multiple tickets, and canceling them if required are considered. © 2022 IEEE. All rights reserved

The Technology Acceptance Model and Learning Management System: A Study on Undergraduate Tourism and Hospitality Students

The roles of educational online tools are very prevalent in the current time due to the advancement in technology, digital transformation, and the better speed of the internet. The digital platform is the most preferable and convenient platform to support advanced educational practices. Being a prominent study tool to manage the lectures, study materials, assignments and other necessary elements related to academics, the learning management system (LMS) has been implemented in most institutions, especially after the lockdown amid the COVID-19, pandemic. The purpose of this paper is to investigate the level of acceptance of the LMS in the North Indian regions of Punjab, Himachal Pradesh, and Haryana with the adoption of the Technology Acceptance Model (TAM) framework. To check the hypotheses (framed as per the TAM model), the structural equation model (SEM) has been applied which reveals that the acceptance level and the adoption of the LMS system is quite low across the chosen population. The complexity and the novelty of technology in addition to the alternative options of LMS can be the reason for the lower level of acceptance and adoption. The exact reason for the lower level of adoption can be explicitly understood from future research. © 2021, Bucharest University of Economic Studies. All rights reserved.

Update on the north american covid-19 myocardial infarction (NACMI) registry

Background: The Coronavirus 2019 (COVID-19) pandemic has impacted ST-segment elevation myocardial infarction (STEMI) care, including timely access to primary percutaneous coronary intervention (PPCI). The goal of The North American COVID-19 and STEMI (NACMI) registry is to describe demographic characteristics, management strategies and outcomes of COVID-19 patients with STEMI. Methods: A prospective, ongoing observational registry was created under the guidance of 3 societies. STEMI patients with confirmed COVID + or suspected (person under investigation or PUI) COVID-19 infection were included. A group of age and sex matched STEMI patients (matched to COVID + in a 2:1 ratio) treated in the pre-COVID era (2015-2019) serves as the control group for comparison of treatment strategies and outcomes. The primary outcome was a composite of in-hospital death, stroke, recurrent myocardial infarction or repeat unplanned revascularization. Results: Current enrollment numbers is comprised of 1,507 patients NACMI (301 COVID +, 604 PUIs and 602 controls). COVID + patients were more likely to have minority ethnicity and have diabetes and undergo medical therapy as primary perfusion therapy (all p <0.001 relative to PUI). Among COVID + patients who received angiography, 71% received PPCI and 23% had no culprit vessels identified on angiography (both p <0.001 relative to controls). The primary outcome occurred in 36% of COVID +, 13% of PUI and 5% of control patients (p<0.001 relative to controls). For the Late Breaking presentation, we will update the numbers of enrolment, present new insights into the ethnic differences, explore patient characteristics in those with no culprit disease and hope to present preliminary results from the EKG and angiographic core lab. Conclusions: COVID + patients with STEMI represent a high-risk group of patients with unique demographic and clinical characteristics and high in-hospital cardiac events.

Is it Safe to Be Transplanted From Living Donors Who Recovered From COVID-19? Experience of 31 Kidney Transplants in a Multicenter Cohort Study From India.

BACKGROUND: There is lack of data on feasibility and safety of kidney transplants from living donors who recovered from COVID-19. METHODS: Here, we present a retrospective cohort study of 31 kidney transplant recipients (KTR) from living donors who recovered from polymerase chain reaction confirmed COVID-19 across 19 transplant centers in India from July 3, 2020, to December 5, 2020. We detailed demographics, clinical manifestations, immunosuppression regimen, treatment, and outcomes. Donors with a previous diagnosis of COVID-19 were accepted after documenting 2 negative polymerase chain reaction tests with complete symptom resolution for at least 28 days and significant social distancing for 14 days before surgery. RESULTS: COVID-19 clinical severity in donors ranged from completely asymptomatic (71%, n = 22) to mild infection (29%, n = 9). None progressed to moderate or severe stages of the disease in the entire clinical course of home treatment. Patient and graft survival was 100%, respectively, with acute cellular rejection being reported in 6.4% (n = 2) recipient. All recipients and donors were asymptomatic with normal creatinine at median follow-up of 44 days after surgery without any complications relating to surgery and COVID-19. CONCLUSIONS: Our data support safety of proceeding with living donation for asymptomatic individuals with comprehensive donor, recipients screening before surgery, using a combination of clinical, radiologic, and laboratory criteria. It could provide new insights into the management of KTR from living donors who have recovered from COVID-19 in India. To the best of our knowledge, this remains the largest cohort of KTR from living donors who recovered from COVID-19.

Poirot: Private contact summary aggregation: Poster abstract

Physical distancing between individuals is key to preventing the spread of a disease such as COVID-19. On the one hand, having access to information about physical interactions is critical for decision makers;on the other, this information is sensitive and can be used to track individuals. In this work, we design Poirot, a system to collect aggregate statistics about physical interactions in a privacy-preserving manner. We show a preliminary evaluation of our system that demonstrates the scalability of our approach even while maintaining strong privacy guarantees. © 2020 Owner/Author.

Peritoneal Dialysis Patients During COVID 19 Pandemic.

COVID pandemic poses challenges to peritoneal dialysis patients, caretaker, and service provider to the PD patients as well. The chronic peritoneal dialysis (PD) patients are trained to do the PD procedure at home, therefore can avoid in-center hospital visit unlike patients on hemodialysis. Thus, PD patients can avoid undue exposure to the novel coronavirus. The PD can be offered in COVID induced AKI patients, even in remote places where hemodialysis cannot be offered. The paper is aimed to provide guidelines about the safe use of PD and treatment of complications during the COVID pandemic.